STUDY PROTOCOL: A MIXED-METHODS STUDY TO EVALUATE WHICH HEALTH VISITING MODELS IN ENGLAND ARE MOST PROMISING FOR MITIGATING THE HARMS OF ADVERSE CHILDHOOD EXPERIENCES

Introduction Exposure to adverse childhood experiences (ACEs) is associated with poorer health outcomes throughout life.In England, health visiting is a long-standing, nationally implemented service that aims to prevent and mitigate the impact of adversity in early childhood, including for children exposed to ACEs.A range of health visiting service

The DNA molecule is exposed to a multitude of damaging agents that can compromise its integrity: single (SSB) and double strand breaks (DSB), intra- or inter-strand crosslinks, base loss or modification, etc.Many different DNA repair pathways coexist in the cell to ensure the stability of the DNA molecule.The nature of the DNA lesion will determine

Imaging with time-of-flight secondary ion mass spectrometry (TOF-SIMS) has expanded very rapidly with the development of gold cluster ion sources (Au3+).It is now possible to acquire ion density maps (ion images) on Necklace Premium Box a tissue section without any treatment and with a lateral resolution of few micrometers.In this article, we have

Dental calculus is an excellent source of information on the dietary patterns of past populations, including consumption of plant-based items.The Lite-Plan HRN Emergency Modules detection of plant-derived residues such as alkaloids and their metabolites in dental calculus provides direct evidence of consumption by individuals within a population.We

Gafchromic films are used as dosimeter for in vivo and in phantom dose measurements.The dose response of Gafchromic EBT2 film under single and repeated exposure conditions is compared in this study to analyze the usability of Gafchromic EBT2 films in cumulative dose measurements.The post-irradiation change in response of the film is studied for up